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Fig. 2 | Journal of Ovarian Research

Fig. 2

From: Exosomes secreted by chemoresistant ovarian cancer cells promote angiogenesis

Fig. 2

a The internalization of IOSE80-exo, SKOV3-exo and SKOV3-DDP-exo (PKH26-labeled, red fluorescence) by HUVECs (Hoechst 33342-labeled, green fluorescence) was examined by confocal laser scanning microscopy. b Proliferation of HUVECs co-cultured with SKOV3-exo, or SKOV3-DDP-exo was measured by CCK-8, cells treated with PBS were served as the control. c-d Migration of HUVECs co-cultured with SKOV3-exo, or SKOV3-DDP-exo was measured by scratch assays. Cells treated with PBS were served as the control. e-f Invasion of HUVECs co-cultured with SKOV3-exo, or SKOV3-DDP-exo was measured by transwell assay, cells treated with PBS were served as the control. g Capillary-like tubes of HUVECs co-cultured with SKOV3-exo, or SKOV3-DDP-exo were measured by tube formation experiment, cells treated with PBS were served as the control. *p < .05, **p < .01, ***p < .001

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