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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: Propofol suppresses cell viability, cell cycle progression and motility and induces cell apoptosis of ovarian cancer cells through suppressing MEK/ERK signaling via targeting circVPS13C/miR-145 axis

Fig. 1

Propofol inhibits the viability, cell cycle and metastasis while triggers the apoptosis of ovarian cancer cells. a The cell viability of A2780 and SKOV3 cells exposed to different concentrations of Propofol (3 μg/mL, 6 μg/mL or 9 μg/mL) for 48 h was analyzed by MTT assay. b-f A2780 and SKOV3 cells were divided into two groups: Control group and Propofol treatment group (6 μg/mL). b and c The percentages of ovarian cancer cells in G0/G1, S and G2/M were measured by flow cytometry. d and e Transwell assays were used to examine the abilities of migration and invasion of ovarian cancer cells (magnification: 100 ×). The ruler in figures indicates 100 μM. f The apoptosis rate (early and late apoptosis) of ovarian cancer cells was analyzed by flow cytometry. *P < 0.05, **P < 0.01, ***P < 0.001

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Journal of Ovarian Research

ISSN: 1757-2215

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