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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: Propofol suppresses cell viability, cell cycle progression and motility and induces cell apoptosis of ovarian cancer cells through suppressing MEK/ERK signaling via targeting circVPS13C/miR-145 axis

Fig. 3

Propofol-induced damage in ovarian cancer cells is attenuated by the addition of anti-miR-145. a After transfecting with anti-NC or anti-miR-145, the expression of miR-145 was detected by qRT-PCR. (B-F) Ovarian cancer cells were divided into three groups, including anti-NC group, Propofol + anti-NC group, Propofol + anti-miR-145 group. b MTT assay was applied to examine the viability of ovarian cancer cells in different groups. c The influence of Propofol and anti-miR-145 in the cell cycle of ovarian cancer cells was analyzed by flow cytometry. d and e The migration ability and invasion ability of ovarian cancer cells were assessed by transwell assays. f The apoptosis rate in different treatment groups was analyzed by flow cytometry. *P < 0.05, **P < 0.01, ***P < 0.001

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