Skip to main content
Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Propofol suppresses cell viability, cell cycle progression and motility and induces cell apoptosis of ovarian cancer cells through suppressing MEK/ERK signaling via targeting circVPS13C/miR-145 axis

Fig. 5

Propofol inhibits the progression of ovarian cancer via circVPS13C/miR-145 axis. a We transfected miR-145 or miR-NC into ovarian cancer cells, and the level of miR-145 was analyzed by qRT-PCR. (B-F) Ovarian cancer cells were divided into four groups, including vector + miR-NC group, Propofol + vector + miR-NC group, Propofol + oe-VPS13C + miR-NC group and Propofol + oe-VPS13C + miR-145 group. b Cell viability was assessed by MTT assay. c Cell cycle was measured by flow cytometry. d and e The migration and invasion capacities of ovarian cancer cells were assessed by transwell assays. f The apoptotic ovarian cancer cells were distinguished from normal or necrotic cells by flow cytometry. *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page

Journal of Ovarian Research

ISSN: 1757-2215

Contact us