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Table 1 Clinical, biochemical and hormonal features of participants

From: The gut microbial composition in polycystic ovary syndrome with insulin resistance: findings from a normal‐weight population

  

PCOS

Parametes

HC(n = 12)

NIR(n = 10)

IR(n = 14)

Age(years)

28.25 ± 1.22

26.4 ± 3.41

26.71 ± 2.43

Menstrual cycle(days)

29.67 ± 2.02AB

82.7 ± 26.61B

75.43 ± 27.91 A

BMI(Kg/m2)

21.28 ± 1.34

21.32 ± 1.22

21.91 ± 1.4

Waist

67.42 ± 4.4AB

71.8 ± 3.29BC

77.79 ± 5.73AC

Hip

88 ± 5.31

87.8 ± 3.33

91.54 ± 4.43

Waist to hip ratio

0.77 ± 0.03AB

0.82 ± 0.03BC

0.85 ± 0.04AC

FPG (mmol/L)

5 ± 0.27 A

5.09 ± 0.47

5.42 ± 0.59 A

FINs(uU/mL)

6.91 ± 1.82 A

6.95 ± 2.52 C

14.81 ± 3.88AC

HOMA-IR

1.54 ± 0.45 A

1.61 ± 0.64 C

3.57 ± 1.07AC

HbA1-C

5.04 ± 0AB

5.37 ± 0.21B

5.26 ± 0.28 A

FSH (IU/L)

6.8 ± 2.18

5.92 ± 2.16

6.43 ± 1.42

LH(IU/L)

6.25 ± 2.88AB

15.55 ± 8.03B

15.37 ± 7.31 A

LH/FSH

0.96 ± 0.4AB

2.53 ± 0.89B

2.42 ± 1.2 A

T (nmol/L)

0.75 ± 0.21AB

1.93 ± 0.57B

1.81 ± 0.82 A

P(nmol/l)

0.54 ± 0.16B

0.93 ± 0.52B

0.74 ± 0.43

E2(pmol/L)

183.51 ± 100.9B

281.47 ± 164.67B

194.25 ± 55.9

AMH

4.99 ± 3.74 A

7.99 ± 2.79

9.28 ± 5.12 A

TBA (umol/l)

4.7 ± 2.22

5.51 ± 4.77

5.26 ± 2.4

ALT (U/L)

13.18 ± 2.7

21.02 ± 15.13

20.81 ± 11.77

AST(U/L)

18.22 ± 5.91

22.03 ± 6.72

21.64 ± 6.4

Lithic (umol/L)

243.43 ± 37.04B

320.21 ± 56.66B

283.65 ± 105.62

TG( mmol/L)

0.88 ± 0.25 A

1.14 ± 0.84

1.29 ± 0.41 A

TC( mmol/L)

4.29 ± 1.11

4.39 ± 0.68

4.77 ± 0.88

HDL(mmol/L)

1.47 ± 0.31

1.36 ± 0.26

1.33 ± 0.23

LDL(mmol/L)

2.67 ± 0.59

2.6 ± 0.53

2.9 ± 0.6

APO-a

93.13 ± 71.68

120.14 ± 126.97

194.49 ± 220.43

ApoA/ApoB

2.47 ± 0.48

2.31 ± 0.56

2.22 ± 0.62

FFA(mmol/L)

0.47 ± 0.11 A

0.48 ± 0.31

0.66 ± 0.24 A

hsCRP(mg/L)

0.69 ± 0.56 A

0.8 ± 0.75 C

1.63 ± 1.27AC

IL-6(pg/ml)

1.13 ± 0.46AB

2.12 ± 0.26B

2.56 ± 1.28 A

TNF

3.76 ± 1.43AB

4.86 ± 1.07B

4.54 ± 0.51 A

  1. A: P < 0.05 for HC vs. IR-PCOS group
  2. B: P < 0.05 for HC vs. NIR-PCOS group
  3. C: P < 0.05 for IR vs. NIR-PCOS group
  4. Abbreviation: PCOS polycystic ovary syndrome; PCOS-IR PCOS with insulin resistance; PCOS-NIR PCOS withoutinsulin resistance; BMI body mass index; WHR the ratio of waist to hip; FSH follicular stimulating hormone; LHluteinizing hormone; TNF-a tumor necrosis factor-a; FPG fasting plasma glucose; FINS fasting plasma insulin;HOMAIR homeostasis model assessment of insulin resistance; PPG 3h postprandial plasma glucose; TC totalcholesterol; HDL-C high density lipoprotein-cholesterol; LDL-C low density lipoprotein-cholesterol; ALT alanine aminotransferase; AST aspartate aminotransferase