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Table 5 Multivariate Cox proportional hazards analysis for PFS and OS used to adjust risk associated prognostic clinical features

From: Ovarian endometrioid carcinoma and clear cell carcinoma: A 21-year retrospective study

Pure group (n = 164)

PFS

OS

 

HR (95%CI)

p-value

HR (95%CI)

p-value

Parity

0.906 (0.508–1.615)

0.738

/

/

CA-125(before)

1.000 (0.999–1.000)

0.595

1.646 (0.403–6.725)

0.487

CA-125(after)

1.002 (1.000–1.005)

0.044

/

/

FIGO

1.722 (0.990–2.994)

0.054

3.981 (1.821–8.706)

0.001

EM-related

4.014 (1.056–15.262)

0.041

0.925 (0.272–3.146)

0.047

Residual disease

0.915 (0.475–1.766)

0.792

1.389 (0.823–2.346)

0.219

Lymph Nodes excision

0.325 (0.078–1.346)

0.325

0.925 (0.272–3.146)

0.900

Mixed group (n = 47)

PFS

OS

 

HR (95%CI)

p-value

HR (95%CI)

p-value

CA-125(before)

1.000 (0.999–1.001)

0.835

1.000 (1.000–1.001)

0.185

CA-125(after)

1.003 (0.998–1.008)

0.235

/

/

FIGO

1.934 (0.211–17.700)

0.023

1.880 (0.699–5.059)

0.211

EM-related

/

/

/

/

Residual disease

1.490 (0.544–4.087)

0.544

1.030 (0.508–2.086)

0.935

Mixed with EC

0.070 (0.014–0.347)

0.001

0.425 (0.107–1.684)

0.223

Appendix excision

4.460 (0.350–56.794)

0.249

0.228 (0.041–1.258)

0.090

Lymph Nodes excision

1.934 (0.211–17.700)

0.559

1.030 (0.508–2.086)

0.935

2–4 stage of patients with pure cancer

PFS

HR (95%CI)

p-value

FIGO

2.918 (1.022–8.326)

0.045

R0

0.287 (0.110–0.749)

0.011

  1. CA Cancer antigen; CA-125(before) CA-125 level before surgery; CI Confidence interval; FIGO International Federation of Gynecology and Obstetrics; HR Hazard ratio; OS Overall survival; PFS Progression-free survival. R0, Achieving optimal cytoreduction and/or removal of all macroscopic disease