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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: RETRACTED ARTICLE: H3K27ac-induced lncRNA PAXIP1-AS1 promotes cell proliferation, migration, EMT and apoptosis in ovarian cancer by targeting miR-6744-5p/PCBP2 axis

Fig. 3

PAXIP1-AS1 was a sponge of miR-6744-5p in OC cells. a Distribution of PAXIP1-AS1 in SKOV3 and OVCAR3 cells was validated by the subcellular fractionation assay. b Predicted miRNAs for PAXIP1-AS1 by DIANA tool. c RT-qPCR analysis of miR-3942-3p, miR-6744-5p, miR-6505-5p, miR-6796-5p and miR-1976 in OC cells. d Binding site of miR-6744-5p on PAXIP1-AS1 sequence. e Overexpression efficiency of miR-6744-5p mimics was tested by RT-qPCR. f Binding of PAXIP1-AS1 to miR-6744-5p was assessed through luciferase reporter assay. g The reaction between PAXIP1-AS1 and Bio-miR-6744-5p-WT or Bio-miR-6744-5p-Mut was evaluated via RNA pulldown assay. *p < 0.05

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Journal of Ovarian Research

ISSN: 1757-2215

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