Cyclin-dependent kinase 9 (CDK9) predicts recurrence in Middle Eastern epithelial ovarian cancer

Table 2 Clinicopathological associations of CDK9 protein expression in EOC

	Total		CDK9 overexpression		CDK9 low expression		p value
	No.	%	No.	%	No.	%
No. of patients	441		248	56.2	193	43.8
Age (Yrs)
≤ 50	221	50.1	129	58.4	92	41.6	0.3649
> 50	220	49.9	119	54.1	101	45.9
Histology Type
High grade Serous	233	52.8	146	62.7	87	37.3	0.0623
Low grade Serous	83	18.8	37	44.6	46	55.4
Mucinous	64	14.5	31	48.4	33	51.6
Endometrioid	40	9.1	22	55.0	18	45.0
Clear cell	10	2.3	5	50.0	5	50.0
Undifferentiated	11	2.5	7	63.6	4	36.4
Histological Grade
Grade 1	98	23.1	46	46.9	52	53.1	0.0758
Grade 2	152	35.8	91	59.9	61	40.1
Grade 3	175	41.2	105	60.0	70	40.0
pT
T1	89	20.4	52	58.4	37	41.6	0.7125
T2	40	9.2	24	60.0	16	40.0
T3	307	70.4	168	54.7	139	45.3
pN
pN0	401	92.0	225	56.1	176	43.9	0.8351
pN1	35	8.0	19	54.3	16	45.7
pM
pM0	358	82.1	181	50.6	177	49.4	< 0.0001
pM1	78	17.9	63	80.8	15	19.2
Stage
I	89	20.4	52	58.4	37	41.6	< 0.0001
II	26	5.9	11	42.3	15	57.7
III	244	55.8	119	48.8	125	51.2
IV	78	17.9	63	80.8	15	19.2
Recurrence
Yes	145	32.9	94	64.8	51	35.2	0.0105
No	296	67.1	154	52.0	142	48.0
Ki-67
High	218	51.5	152	69.7	66	30.3	< 0.0001
Low	205	48.5	88	42.9	117	57.1

ISSN: 1757-2215