Fig. 3
From: TCP1 regulates PI3K/AKT/mTOR signaling pathway to promote proliferation of ovarian cancer cells
Growth-inhibiting role of knockdown TCP1 in A2780 cell lines. A The MTT assay showed that with a dramatic decrease of TCP1 expression, the proliferation of A2780 cells was significantly inhibited as shown by a nearly flat growth curve. The difference arose from Day 1 and persisted until Day 4. B Colony-formation assays indicated decreased growth rates in TCP1-KD A2780 cell line. C The colony-formation abilities from (B). One independent experiment was carried out in triplicate. Values are shown as the mean ± standard deviation (SD). Use independent Student’s t-test to calculate P-values. ***P < 0.001 vs. the NC