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Table 2 Association between HE4 levels a and tomographic response (n = 53)

From: Kinetics of HE4 and CA125 as prognosis biomarkers during neoadjuvant chemotherapy in advanced epithelial ovarian cancer

 

Univariable

Multivariableb

HE4

Estimated

CI 95%

p

Estimated

CI 95%

p

Basal

-0244

-0.689, 0.151

0.357

-0.262

-0.832, 0.308

0.367

To the first cycle

0.444

-0-249, 0.561

0.119

0.524

-0.077, 1.125

0.088

To the second cycle

0.676

0.061, 1.081

0.054

0.752

0.028, 1.475

0.044

To the third cycle

0.766

0.175, 1.181

0.042

0.843

0.068, 1.617

0.033

All values

0.241

0.012, 0.352

0.038

0.268

0.030, 0.505

0.027

  1. CI confidence interval
  2. a Transformed by decimal logarithm. Measurements of all cycles and basal values were included
  3. b Adjusted for age at diagnosis, baseline ECOG, smoking the histological subtype and FIGO stage
  4. Those p values with statistical significance (less than 0.05) are marked in bold