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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Pharmacological inhibition of the PI3K/PTEN/Akt and mTOR signalling pathways limits follicle activation induced by ovarian cryopreservation and in vitro culture

Fig. 5

General overview of follicle activation induced by cryopreservation and in vitro culture. PI3K/PTEN/Akt and mTOR pathways are implicated in follicle activation in murine ovaries after cryopreservation and/or in vitro culture via an increase of p-Akt and p-rps6. LY294002 and rapamycin can limit this follicle activation

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