Fig. 2

LINC01503 depletion attenuates CBP resistance in CBP-resistant OCa cells. A LINC01503 expression was measured by RT-qPCR in OVCAR-3/CBP and CAOV-3/CBP cells transfected with si-negative control (NC) or si-LINC01503. B CCK-8 assay was used to measure the IC50 value in CBP-resistant OCa cells transfected with si-NC or si-LINC01503. D Western blot showed the protein levels of MRP1 and MRP2 in CBP-resistant OCa cells transfected with si-NC or si-LINC01503. E Colony formation assay was used to detect the proliferation of CBP-resistant OCa cells transfected with si-NC or si-LINC01503. F and G Transwell assay was performed to detect the migration and invasion of CBP-resistant OCa cells transfected with si-NC or si-LINC01503. H Western blot showed the expression of E-cadherin, N-cadherin and Vimentin in CBP-resistant OCa cells. I Flow cytometry assay was performed to detect the apoptosis of CBP-resistant OCa cells transfected with si-NC or si-LINC01503. J Western blot showed the expression of Bax, Bcl-2, and cleaved caspase-3 in CBP-resistant OCa cells. (n = 3; *P < 0.05, **P < 0.01, ***P < 0.001)