Table 3 Univariate and multivariate cox hazards survival analysis for overall survival (OS) in epithelial ovarian cancer (EOC) patients
From: Clinical significance for combined coagulation indexes in epithelial ovarian cancer prognosis
Variables | Univariate regression analysis | Multivariate regression analysis | ||
|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age | 1.327(1.089–1.948) | 0.037 | 1.273(1.048–2.047) | 0.045 |
BMI | 1.291(0.894–1.473) | 0.248 | - | - |
Tumor size | 1.561(1.210–1.826) | 0.028 | 1.534(0.987–1.932) | 0.132 |
Pathological grade | ||||
 G1-2 | Reference | - | Reference | - |
 G3 | 1.356(1.130–1.825) | 0.019 | 1.419(1.102–2.491) | 0.032 |
Clinical stage | ||||
 I-II | Reference | - | Reference | - |
 III-IV | 1.938(1.420–3.487) | 0.015 | 2.038(1.284–3.768) | 0.008 |
Histological type | ||||
 Serous | Reference | - | - | - |
 Others | 1.241(0.948–1.462) | 0.183 | - | - |
Neutrophil | 1.382(1.039–1.826) | 0.046 | 1.276(0.983–1.850) | 0.221 |
lymphocyte | 0.892(0.652–1.024) | 0.078 | - | - |
Platelet | 1.352(0.846–1.745) | 0.328 | - | - |
Fibrinogen | 1.537(1.241–1.938) | 0.025 | 1.420(0.995–2.018) | 0.089 |
CA-125 | 1.432(1.129–1.726) | 0.019 | 1.426(1.103–1.894) | 0.038 |
CA-199 | 1.138(1.037–1.655) | 0.043 | 1.123(0.913–1.748) | 0.347 |
AFP | 1.328(0.784–1.526) | 0.361 | - | - |
CEA | 1.241(0.848–1.657) | 0.497 | - | - |
HE4 | 1.452(0.913–1.728) | 0.142 | - | - |
DD-INR group | ||||
 0 | Reference | - | Reference | - |
 1 | 1.653(1.210–1.923) | 0.007 | 1.536(1.129–2.031) | 0.013 |
 2 | 2.390(1.738–2.872) | 0.001 | 2.412(1.683–3.241) | 0.009 |
APTT | 0.783(0.482–0.929) | 0.047 | 0.820(0.421–1.532) | 0.492 |
TT | 0.803(0.562–1.118) | 0.193 | - | - |