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Fig. 5 | Journal of Ovarian Research

Fig. 5

From: Knockdown of circ-FURIN suppresses the proliferation and induces apoptosis of granular cells in polycystic ovary syndrome via miR-195-5p/BCL2 axis

Fig. 5

Effects of circ-FURIN and BCL2 on KGN cell proliferation and apoptosis. A The empty vector and BCL2 overexpressing vector were transfected into KGN cells, and RT-qPCR was conducted to examine BCL2 levels. Post-transfection, B cell proliferation was assessed by MTT assay and (C) cell colony formation assay (D) Flow cytometry was used to analyze cell apoptosis. E Caspase-3, Bax, and p-PI3K levels were conducted by western blot. ##P < 0.01. **P < 0.01

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