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Fig. 3 | Journal of Ovarian Research

Fig. 3

From: Long noncoding RNA SNHG25 promotes the malignancy of endometrial cancer by sponging microRNA-497-5p and increasing FASN expression

Fig. 3

SNHG25 directly sponged iR-497-5p in EC. A The subcellular location of SNHG25 in EC cells. B, C The expression levels of miR-195-5p, miR-296-3p, miR-424-5p, and miR-497-5p in uterine corpus endometrial carcinoma were examined using the TCGA database. D The expressions of miR-195-5p, miR-296-3p, miR-424-5p, and miR-497-5p were examined in SNHG25-silenced EC cells. E The interacting sequences between SNHG25 and miR-497-5p were predicted via bioinformatic analysis. F Luciferase activity was measured in EC cells transfected with SNHG25-wt or SNHG25-mut in parallel with miR-497-5p/NC mimic. G RIP assay was used to validate the interaction between SNHG25 and miR-497-5p. H qRT-PCR was used for measuring miR-497-5p expression in EC tissues. I The correlation between miR-497-5p and SNHG25 expression in EC tissues. **P < 0.01

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