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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: RNA-binding protein IGF2BP2 enhances circ_0000745 abundancy and promotes aggressiveness and stemness of ovarian cancer cells via the microRNA-3187-3p/ERBB4/PI3K/AKT axis

Fig. 1

Circ_0000745 is abundantly expressed OC tissues and cells. A, sequence information of circ_0000745; B, expression of circ_0000745 in OC tumor tissues and the paired para-cancerous tissues examined by RT-qPCR; C, expression of circ_0000745 in the OC cell lines (CoC1, ES-2, SW626 and SK-OV-3) and in normal epithelial ovarian cells (IOSE-80) quantified by RT-qPCR; D, stability of circ_0000745 in OC cells examined by RNase R treatment. Data were exhibited as mean ± SD from three repetitions. Differences were analyzed by paired t test (B), one-way ANOVA (C) or two-way ANOVA (D); *p < 0.05 vs. adjacent; #p < 0.05 vs. IOSE-80 cells; & p < 0.05 vs. RNase-R

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