Fig. 1

miR-149-3p was overexpressed in OC and associated with poor survival. A. The volcano plot of differentially expressed miRNAs in GSE79943 and GSE131790. B. Wayne-diagram analysis of up-regulated miRNAs in GSE79943 and GSE131790. C. Heatmap of five intersected miRNAs in GSE79943 and GSE131790. D. miR-149-3p expression in OC tissues from patients with tumor residual. E. Kaplan-Meier analysis was applied to assess the relationship between miR-149-3p and survival. F. miR-149-3p expression was detected in OC tissues (n = 25) and normal ovarian tissues (n = 15) by qPCR. G. miR-149-3p expression was detected in cases with metastasis (n = 15) or without metastasis (n = 10) by qPCR. H. miR-149-3p expression was detected in chemosensitive and chemoresistant OC tissues (n = 15) by qPCR. I. miR-149-3p expression was detected in OC cells by qPCR. *P < 0.05. All experiments were repeated three times with similar results