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Table 4 Univariate and multivariate Cox regression analyses of potential prognostic factor for progression-free survival (PFS) in patients with serous ovarian carcinoma

From: Co-expression of cancer stem cell markers, SALL4/ALDH1A1, is associated with tumor aggressiveness and poor survival in patients with serous ovarian carcinoma

Covariate

Univariate analysis

Multivariate analysis

HR (95% CI)

P-value

HR (95% CI)

P-value

SALL4/ ALDH1A1

coexpression

High versus Low

3.018 (1.091- 8.344)

0.033

4.095 (1.295- 12.952)

0.016

Histological grade

 

0.025

 

0.770

 II versus I

1.863 (0.192- 18.045)

0.974

0.010 (0.100- 2.222)

0.964

 III versus I

5.848 (1.636- 20.899)

0.007

1.922 (0.326- 11.348)

0.471

 FIGO stage

 

0.017

 

0.192

 II versus I

0.575 (0.081- 4.090)

0.581

0.601 (0.077- 4.677)

0.627

 III versus I

3.921 (0.867- 17.737)

0.076

3.501 (608- 20.175)

0.161

Vascular invasion (VI)

0.286 (0.086- 0.956)

0.042

–

–

Cervix involvement

0.182 (0.057- 0.582)

0.004

–

–

 Myometrium involvement

0.207 (0.065- 0.656)

0.007

–

–

 Vagina involvement

0.250 (0.080- 0.777)

0.017

–

–

 Colon involvement

0.314 (0.105- 0.934)

0.037

–

–

 Post-cul-de-sac involvement

0.177 (0.054- 0.579)

0.004

–

–

Distant metastasis

0.111 (0.025- 0.490)

0.004

–

–

Tumor recurrence

0.012 (0.000- 0.810)

0.040

–

–

  1. H-score histological score
  2. Values in bold are statistically significant
  3. The variables with P value less than 0.05 and HR more than 1.0 were included in multivariable analyses HR hazard ratio, CI confidence interval