Fig. 6

Reduction of ITGA6 suppresses the malignancy of OC cells. A-B ITGA6 expression in OC cells was detected by Western blot; C-D the transfection efficacy of si-ITGA6 was verified by Western blot; E viability of SKOV3 and A2780 cells was detected by CCK-8 assay; F expression of EMT-related proteins in OC cells was measured by RT-qPCR; G colony formation ability of SKOV3 and A2780 cells was detected by colony formation assay; H Transwell assay was employed to determine the invasion ability of SKOV3 and A2780 cells; I migration ability of SKOV3 and A2780 cells was evaluated by scratch test; J apoptosis rates of SKOV3 and A2780 cells were measured by flow cytometry; * P < 0.05 vs IOSE, + P < 0.05 vs the si-NC group; the data were expressed as mean ± standard deviation, t-test was performed for comparisons between two groups, ANOVA was used for comparisons among multiple groups