Table 2 Univariate and Multivariate Analysis of Overall Survival in the Training Group
From: A prognostic model of patients with ovarian mucinous adenocarcinoma: a population-based analysis
Variables | Number of patients | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | ||
Age | |||||
12–57 | 578 | Reference | Reference | ||
58–70 | 213 | 1.465 (1.081–1.986) | 0.014 | 1.508 (1.091–2.085) | 0.012 |
71–92 | 126 | 3.695 (2.773–4.923) | < 0.001 | 3.254 (2.292–4.620) | < 0.001 |
Race | |||||
Black | 70 | Reference | Reference | ||
White | 742 | 0.520 (0.360–0.752) | < 0.001 | 0.510 (0.345–0.754) | < 0.001 |
Other | 105 | 0.331 (0.191–0.572) | < 0.001 | 0.500 (0.284–0.883) | 0.017 |
Marital | |||||
Divorced | 94 | Reference | Reference | ||
Married | 461 | 0.761 (0.514–1.127) | 0.173 | 0.772 (0.509–1.170) | 0.222 |
Separated | 5 | 1.047 (0.250–4.370) | 0.950 | 0.764 (0.167–3.510) | 0.730 |
Single | 265 | 0.581 (0.375–0.898) | 0.015 | 0.754 (0.475–1.197) | 0.232 |
Unmarried or Domestic Partner | 1 | 1.689*10^(−6)(0-Inf) | 0.992 | 8.143*10^(−6)(0-Inf) | 0.998 |
Widowed | 91 | 1.487 (0.939–2.356) | 0.091 | 0.644 (0.383–1.081) | 0.096 |
Laterality | |||||
unilateral | 807 | Reference | Reference | ||
bilateral | 110 | 5.387 (4.135–7.019) | < 0.001 | 1.258 (0.909–1.741) | 0.166 |
Grade | |||||
I | 349 | Reference | Reference | ||
II | 405 | 1.419 (1.051–1.916) | 0.023 | 1.215 (0.892–1.656) | 0.218 |
III | 132 | 3.249 (2.329–4.533) | < 0.001 | 2.138 (1.471–3.106) | < 0.001 |
IV | 31 | 2.533 (1.401–4.580) | 0.002 | 2.347 (1.255–4.388) | 0.008 |
T stage | |||||
T1 | 684 | Reference | Reference | ||
T2 | 66 | 3.515 (2.336–5.289) | < 0.001 | 2.305 (1.465–3.626) | < 0.001 |
T3 | 166 | 10.780 (8.269–14.055) | < 0.001 | 6.290 (4.290–9.222) | < 0.001 |
TX | 1 | 2.146*10^(−6)(0-Inf) | 0.994 | 2.473*10^(− 7)(0-Inf) | 0.996 |
N stage | |||||
N0 | 842 | Reference | Reference | ||
N1 | 42 | 5.500 (3.799–7.964) | < 0.001 | 1.560 (1.030–2.363) | 0.036 |
NX | 33 | 4.657 (3.023–7.172) | < 0.001 | 1.525 (0.927–2.508) | 0.096 |
M stage | |||||
M0 | 832 | Reference | Reference | ||
M1 | 72 | 10.335 (7.715–13.843) | < 0.001 | 2.900 (2.046–4.112) | < 0.001 |
MX | 13 | 5.042 (2.665–9.537) | < 0.001 | 2.158 (1.045–4.456) | 0.038 |
CA125 | |||||
Positive | 612 | Reference | Reference | ||
Negative | 302 | 0.273 (0.192–0.389) | < 0.001 | 0.520 (0.353–0.767) | < 0.001 |
Borderline | 3 | 1.946*10^(−7)(0-Inf) | 0.992 | 3.821*10^(−7)(0-Inf) | 0.993 |
Surgery | |||||
No | 5 | Reference | Reference | ||
Yes | 912 | 0.096 (0.040–0.236) | < 0.001 | 0.908 (0.342–2.413) | 0.847 |
Radiation | |||||
Yes | 6 | Reference | Reference | ||
None/Unknown | 911 | 0.187 (0.077–0.453) | < 0.001 | 0.998 (0.388–2.562) | 0.996 |
Chemotherapy | |||||
Yes | 427 | Reference | Reference | ||
No/Unknown | 490 | 0.616 (0.482–0.788) | < 0.001 | 1.729 (1.262–2.371) | < 0.001 |