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Table 1 Ovarian reserve of eggs determined by the number of ovarian follicles at different stages of development

From: Super-critical fluid extract of Bryonopsis laciniosa (Shivlingi) seeds restores fertility in zebrafish models through revival of cytological and anatomical features

  Study Groups Control Fertility impaired model Letrozole (0.036 µg/kg) SLSO (µg/kg)
0.25 0.64 1.28 6.4 12.8 128
Follicle count—Ovarian Reserve of Eggs Primary growth (PG) 114 ± 8.2 97 ± 6.8#### 137 ± 7**** 99 ± 9.2 113 ± 8.5**** 320 ± 6.9**** 352 ± 5.9**** 458 ± 7.9**** 389 ± 9.8****
Pre-Vitellogenic (PV) 296 ± 8.1 79 ± 8.9#### 256 ± 7.7**** 83 ± 8.5 94 ± 6.3**** 490 ± 6.9**** 291 ± 7.9**** 125 ± 8.4**** 131 ± 6.6****
Early Vitellogenic (EV) 311 ± 8.3 16 ± 6.8#### 140 ± 7.4**** 27 ± 8.5**** 31 ± 7.8**** 34 ± 7.5**** 39 ± 7.4**** 208 ± 8.4**** 264 ± 7.5****
Mid-Vitellogenic (MV) 109 ± 7.8 9 ± 7.6#### 96 ± 8.4**** 10 ± 5.8 20 ± 6.3**** 31 ± 8.0**** 28 ± 7.2**** 49 ± 7.0**** 64 ± 9.1****
Final growth (FG) 483 ± 7.6 12 ± 6#### 356 ± 7.6**** 31 ± 7.1**** 91 ± 8.0**** 119 ± 7.7**** 196 ± 8.4**** 321 ± 8.6**** 401 ± 7.8****
Total 1313 ± 16.3 213 ± 15.3#### 985 ± 18.0**** 250 ± 17.0**** 348 ± 18.4**** 993 ± 15.6**** 906 ± 18.4**** 1161 ± 17.6**** 1249 ± 19.0****
  1. Data represented as mean ± SD (n = 24). Statistical significance was arrived at using ANOVA followed by Tukey’s multiple comparison test
  2. #### represents p < 0.0001 compared to normal control, **** represents p < 0.0001 compared to the fertility impaired group