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Table 5 IVF cycle characteristics and outcomes in patients with unoperated OMAs according to the cyst size

From: The presence of ovarian endometrioma adversely affect ovarian reserve and response to stimulation but not oocyte quality or IVF/ICSI outcomes: a retrospective cohort study

Variable

Endometrioma size < 40 mm (n = 72)

Endometrioma size ≥ 40 and < 60 mm (n = 18)

Endometrioma size ≥ 60 mm (n = 14)

P value

Age (years)

33.64 ± 3.89

33.33 ± 3.53

35.23 ± 3.92

0.324

BMI (kg/m2)

21.56 ± 2.71

20.89 ± 23.19

21.58 ± 3.25

0.671

Duration of infertility (years)

2.82 ± 1.84

3.14 ± 2.82

2.77 ± 2.01

0.830

AMH (ng/mL)

3.18 ± 2.86

2.38 ± 1.66

2.19 ± 2.81

0.332

AFC (n)

9.56 ± 5.31

8.94 ± 5.42

3.85 ± 3.31 ****

0.002

Basal FSH (IU/L)

9.22 ± 5.73

12.44 ± 11.89

12.92 ± 7.73

0.114

Basal E2 (pg/ml)

86.50 ± 201.05

96.15 ± 135.79

51.77 ± 40.58

0.772

Duration of stimulation (days)

10.01 ± 2.23

9.33 ± 3.41

8.39 ± 3.52

0.107

Total Gn administered (IU)

3020.49 ± 1071.67

2668.75 ± 1090.75

2284.62 ± 1248.48*

0.064

E2 on day of hCG (pg/ml)

3265.05 ± 2596.00

3084.31 ± 2015.99

1589.90 ± 1626.60*

0.132

Number of follicles ≥ 10 mm on day of hCG

12.67 ± 9.01

11.33 ± 8.94

6.92 ± 7.94*

0.103

Number of oocytes retrieved (n)

10.17 ± 7.08

8.77 ± 5.13

5.08 ± 5.14 *

0.039

OSI

4.13 ± 3.89

3.51 ± 2.16

2.34 ± 1.83

0.220

Number of MII oocytes (n)

8.46 ± 6.28

7.41 ± 4.23

4.31 ± 4.44*

0.062

Oocyte maturity rate % (n)

83.20 (609/732)

84.56 (126/149)

84.85 (56/66)

0.879

Number of fertilized oocytes (n)

7.60 ± 5.84

6.77 ± 4.09

3.39 ± 3.57 *

0.037

Fertilization rate (%)

82.32 (517/628)

86.49 (96/111)

69.49 (41/59) *

0.020

Number of embryos (n)

7.63 ± 5.99

7.12 ± 3.98

3.54 ± 4.05*

0.052

Number of transplantable embryos (n)

6.94 ± 5.58

6.47 ± 3.69

2.92 ± 3.86 *

0.038

Number of top-quality embryos (n)

2.79 ± 2.82

2.53 ± 2.03

1.15 ± 1.21*

0.112

Implantation rate % (n)

35.67 (56/157)

34.78 (8/23)

50 (8/16)

0.566

Cumulative CPRs % (n)

60.32 (38/63)

62.50 (10/16)

41.67 (5/12)

0.452

Cumulative LBRs % (n)

58.73 (37/63)

62.50 (10/16)

41.67 (5/12)

0.490

  1. BMI, body mass index; AMH, anti-Müllerian hormone; AFC, Antral Follicular Count; E2, estradiol; FSH, follicle-stimulating hormone; Gn, gonadotropin; hCG, human chorionic gonadotropin; OSI, Ovarian sensitivity index; FET, Frozen-thawed ET; MII, Metaphase II, CPRs, Clinical pregnancy rates; LBRs, Live birth rates. Values are expressed as n (%), percentage (%) or mean ± standard deviation (SD) unless otherwise stated. P < 0.05 depicts statistical significance. * depicts P < 0.05 when compared with group (Endometrioma size < 40). ** depicts P < 0.01 when compared with group (Endometrioma size < 40). *** depicts P < 0.001 when compared with group (Endometrioma size < 40). **** depicts P < 0.0001 when compared with group (Endometrioma size < 40).