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Table 4 Multivariable analysis of the association of the variables with moderate-to-severe OHSS

From: Retrospective analysis of GnRH-a prolonged protocol for in vitro fertilization in 18,272 cycles in China

Independent covariates

Covariate strata

Crude OR (95% CI)

P-value

Adjusted OR (95% CI)

P-value

Age

 

0.93 (0.91–0.96)

< 0.0001

0.99 (0.96–1.02)

0.5496

BMI

 

0.92 (0.88–0.96)

< 0.0001

0.91 (0.87–0.95)

< 0.0001

AFC

 

1.10 (1.08–1.11)

< 0.0001

1.08 (1.06–1.10)

< 0.0001

No. retrieved oocytes

 

Group 1 to Group 2

25.94 (9.64–69.8)

< 0.0001

15.06 (5.57–40.76)

< 0.0001

 

Group 1 to Group 3

42.79 (15.77–116.12)

< 0.0001

21.24 (7.65–58.96)

< 0.0001

ET strategy

 

All embryos frozen

1

 

1

 
 

1 D3 embryo transferred

0.29 (0.14–0.57)

0.0012

0.60 (0.28–1.29)

0.1020

 

1 blastocyst (Day 5/6 embryo) transferred

1.08 (0.70–1.67)

0.1246

0.82 (0.51–1.32)

0.3396

 

2 D3 embryos transferred

0.85 (0.65–1.11)

0.5886

1.32 (0.95–1.83)

0.1812

 

2 blastocysts transferred

1.04 (0.25–4.32)

0.5998

1.78 (0.42–7.55)

0.3529

  1. P-values correspond to differences determined by Cox regression analyses, with moderate-to-severe OHSS as the outcome (dependent) variable
  2. AFC Antral follicle count, BMI Body mass index, ET Embryo transfer, CI Confidence interval, OHSS Ovarian hyperstimulation syndrome