Table 1 Baseline characteristics of the study groups. The number of patients per group is indicated in the table heading. ARA – advanced reproductive age (>37yo), No ARA – not advanced reproductive age (<37yo)

Oocyte Age (years)

37.6 ± 3.6 (27–45)

39.8 ± 0.2 (37–45)

33.7 ± 0.2 (27–36)

32.8 ± 0.8 (27–36)

34.0 ± 0.3 (27–36)

Sperm Age (years)

39.6 ± 6.1 (26–60)

41.8 ± 0.6 (32–60)

36.2 ± 0.4 (26–44)

34.0 ± 1.2 (26–44)

37.1 ± 0.5 (31–44)

BMI (kg/m²)

24.1 ± 5.0 (14.8–52.8)

24.2 ± 0.4 (14.8–44.5)

24.1 ± 0.7 (16.7–52.8)

27.7 ± 1.7 (21.3–48.1)

23.6 ± 0.8 (16.7–52.8)

AMH (pmol/L)

12.3 ± 7.9 (0.5–40)

11.2 ± 0.8 (2–40)

13.7 ± 0.9 (0.5–40)

19.2 ± 1.6 (10.6–33.6)

13.3 ± 1.1 (0.5–40)

Total Gonadotropin (IU)

3801.9 ± 1065.4 (1050–6675)

3711.4 ± 110.0 (1050–6675)

3913.7 ± 105.1 (1950–6675)

3900.8 ± 201.9 (2400–4875)

3981.6 ± 140.1 (2400–6675)

Estradiol on Trigger (pmol/L)

8954.4 ± 6484.3 (1171–38,825)

7631.6 ± 494.9 (1171–32,335)

10,737.2 ± 883.4 (2108–38,825)

13,256.3 ± 2474.4 (4459–38,825)

10,523.7 ± 1103.0 (2108–29,778)

Trigger to OPU (h)

35.9 ± 0.8 (34.2–38.7)

36.0 ± 0.1 (34.8–38.7)

35.8 ± 0.1 (34.2–37.5)

36.0 ± 0.2 (35–37.5)

35.9 ± 0.1 (34.2–37.5)

OPU to Denudation (h)

1.4 ± 1.1 (0.1–5.5)

1.1 ± 0.1 (0.1–4.4)

1.7 ± 0.1 (0.3–5.5)

1.1 ± 0.2 (0.3–2.5)

1.9 ± 0.2 (0.3–5.5)

Denudation to ICSI (h)

1.2 ± 0.7 (0.1–5.2)

1.1 ± 0.1 (0.1–4.8)

1.2 ± 0.1 (0.1–5.2)

1.2 ± 0.2 (0.1–3.0)

1.2 ± 0.1 (0.5–2.2)