Fig. 5

Construction of Pyrsig score and exploring the relationship between Pyrsig score and clinical features. A, B The relationship between survival outcome and Pyrsig score in patients from TCGA and five GEO cohorts (Log-rank test, P < 0.001). C, D Level of Pyrsig score in two PACs and three gene clusters (Kruskal-Wallis H test, P < 0.01). E Distributions of two PACs, three gene clusters, Pyrsig scores and survival outcomes in OC from TCGA-OV and five GEO cohorts with Alluvial diagram F Survival analysis of patients with low and high TMB in TCGA-OV cohort with Kaplan-Meier. G Difference in prognostic advantages among four groups stratified by Pyrsig score and TMB in TCGA-OV cohort shown by Kaplan-Meier curves (Log-rank test, P = 0.005). H, I Somatic mutation features established with low and high Pyrsig scores by waterfall plot. H-TMB: High tumor mutation burden; L-TMB: Low tumor mutation burden