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Table 2 Features of peritoneal dissemination and residual disease among 59 advanced HGSOC patients in association with the pre-treatment serum CA125-Tn level

From: Evaluation of serum CA125-Tn glycoform in peritoneal dissemination and surgical completeness of high-grade serous ovarian cancer

Parameter

n (%)

CA125-Tn

Median (IQR)

CA125

Median (IQR)

PIV

 0

9 (15.3%)

0.202 (0.157-0.262)

507.5 (137.9-976.7)

 2

10 (16.9%)

0.268 (0.169-0.615)

344.2 (181.4-1387.0)

 4

8 (13.6%)

0.313 (0.227-0.551)

255.2 (179.5-367.1)

 6

18 (30.5%)

0.339 (0.207-0.691)

706.8 (443.5-910.0)

 8

11 (18.6%)

0.915 (0.411-1.309)

1659.0 (375.4-2944.0)

 10

3 (5.1%)

0.926 (0.461-1.248)

2693.0 (573.6-5000.0)

 P-value

 

0.004

0.039

PIV category

 PIV <8

45 (76.3%)

0.315 (0.182-0.594)

507.5 (197.3-910.0)

 PIV ≥8

14 (23.7%)

0.919 (0.461-1.248)

2010.5 (466.8-2944.0)

 P-value

 

0.0001

0.005

Peritoneal dissemination pattern

 Pelvic

3 (5.1%)

0.182 (0.096-0.536)

507.5 (137.9-1151.0)

 Lower abdominal

16 (27.1%)

0.235 (0.163-0.382)

350.6 (175.1-1013.4)

 Upper abdominal or miliary

40 (67.8%)

0.479 (0.316-0.916)

634.5 (297.7-1655.5)

 P-value

 

0.011

0.234

Residual disease

 0

17 (28.8%)

0.220 (0.157-0.411)

328.8 (168.8-976.7)

 ≤1cm

22 (37.3%)

0.350 (0.207-0.606)

627.3 (258.0-1652.0)

 >1cm

20 (33.9%)

0.694 (0.355-1.001)

634.5 (373.9-2176.0)

 P-value

 

0.005

0.129

  1. HGSOC high-grade serous ovarian cancer, IQR interquartile range, PIV predictive index value