Fig. 2

Model construction of genomic features. A Fragment size distributions of OC and HC individuals . A reproducible peak in fragment length at 167 bp (black dashed line) is consistent with association with chromatosomes. B Box plots showing average insert size of healthy individuals (n = 50) is longer than that of patients with ovarian cancer (n=40). C Box plot analysis of Top ten representative motifs showing differential frequencies between OC and HC subjects. D Principal Component Analysis(PCA) of training set(including 50HC,40 OC). E Heat map classification using 209 genes with different nucleosome distribution. F KEGG analysis of 209 genes