Fig. 5

HMGB1 expression in neonatal mouse germ cells Double immunofluorescence of HMGB2 (green) and HMGB1 (red) in paraffin-embedded ovary sections of WT and HMGB2-KO mice at PNDs 0, 3 and 7 (A). Boxed areas were enlarged in the right panel. In WT mouse ovary, all germ cells expressed HMGB2, but not HMGB1 (yellow arrows). In HMGB2-KO mouse ovary, HMGB1 was expressed in germ cells (white arrows). Scale bar 50 µm. qPCR analysis of HMGB2 (B) and HMGB1 mRNA (C) in WT and HMGB2-KO mice at PND 7.