Fig. 6
From: Pivotal role of High-Mobility Group Box 2 in ovarian folliculogenesis and fertility
Expression of HMGB2 and HMGB1 in oocytes Immunofluorescence for HMGB2 (green), HMGB1 (red), and DDX4/MVH (blue) in paraffin-embedded ovary sections of WT and HMGB2-KO mice at 2 and 6 months of age (A). In 2-month-old HMGB2-KO mouse ovary, HMGB1 was expressed in oocyte nuclei (yellow arrows). In 6-month-old HMGB2-KO mouse ovary, HMGB1 expression was depleted (white arrows). Scale bar 50 µm. Western blotting of HMGB1 in mouse ovaries at 2- and 6-months-old WT and HMGB2-KO (B).