Table 2 Ovarian stimulation response among all subjects in general and stratified
Correctly Stimulated | Over-Stimulated | Failed to Stimulate | |
|---|---|---|---|
Overall 157 subjects | 49% | 45.4% | 5.6% |
Serum AMH Stratified (N = 84) | |||
AMH ≥ 1.5 ng/ml | |||
FD dose 2- 3 mcg (N = 29) | 79% | 17.6% | 3.4% |
FD doses > 3 -12mcg (N = 29) | 20% | 62% | 18% |
AMH < 1 ng/ml | |||
FD dose ≤ 4 mcg (N = 5) | 75% | 25% | 0% |
FD doses 6–12 mcg (N = 31) | 29% | 48% | 23% |
FD dose 4- < 6 mcg (N = 0) | NA | NA | NA |
AMH ≥ 1 and < 1.5 ng /ml | |||
FD dose 3–12 mcg (N = 19) | 53% | 47% | 0% |
FD dose 3-6mcg (N = 9) | 67% | 33% | 0% |
FD dose 3–4 mcg (N = 6) | 80% | 20% | 0% |
FD dose 7–12 mcg (N = 10) | 40% | 60% | 0% |
FD dose 6–7 mcg (N = 0) | NA | NA | NA |
AFC Stratified (N = 134) | |||
AFC ≥ 10 | |||
FD dose 2–12 mcg (N = 78) | 52% | 40% | 8% |
FD dose > 3 mcg (N = 37) | 29% | 60% | 11% |
FD dose 2- 3 mcg (N = 41) | 73% | 24.6% | 2.4% |
AFC < 6 | |||
FD dose 3–12 mcg (N = 36) | 44% | 50% | 6% |
FD dose 3- 4 mcg (N = 6) | 50% | 50% | 0% |
FD dose > 4–12 (N = 30) | 44% | 47% | 9% |
FD dose 3 mcg (N = 3) | 100% | 0% | 0% |
AFC 6–9 | |||
FD dose 3–12 mcg (N = 12) | 25% | 75% | 0% |
FD dose 6–12 mcg (N = 17) | 12% | 88% | 0% |
FD dose 3mcg (N = 3) | 100% | 0% | 0% |
Body Weight Stratified (N = 71) | |||
Weight ≥ 80 kg | |||
FD dose 3–12 mcg (N = 26) | 50% | 27% | 23% |
FD dose 4–6 mcg (N = 20) | 50% | 25% | 25% |
FD dose > 6 mcg (N = 6) | 50% | 33% | 17% |
Weight < 80 kg | |||
FD dose 2–12 mcg (N = 45) | 47% | 53% | 0% |
FD dose 2–4 mcg (N = 17) | 71% | 29% | 0% |
FD dose 5.33–12 mcg (N = 28) | 29% | 71% | 0% |
FD dose 4–5.33 (N = 0) | NA | NA | NA |