Fig. 3From: Androgen increases klotho expression via the androgen receptor-mediated pathway to induce GCs apoptosisAndrogen stimulates AR and klotho expression in ovary but flutamide can converse this situation Immunohistochemistry (A, B), Western blot (E, F) were used to detect the expression of AR in ovary. The results showed that the expression of AR and klotho were increased. However, using flutamide treatment for 15 days, both Immunohistochemistry (C, D) and Western blot (G, H) were showed the decreased expression of AR and klotho. G ** P < 0.01 vs. Control; H * P < 0.05 vs. Control, ** P < 0.01 vs. ControlBack to article page