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Fig. 1 | Journal of Ovarian Research

Fig. 1

From: GIMAP7 induces oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inhibiting sonic hedgehog signalling pathway

Fig. 1

GIMAP7 expression is upregulated in PCOS rat. A The GIMAP7 expression in patients without PCOS (n = 4) and with PCOS (n = 4) from GEO dataset GSE80432. B-D: Sprague–Dawley rats (n = 6 per group) were injected with DHEA for constructing PCOS animal models. The rats in the blank group were injected with same volume of sesame oil. GIMAP7 mRNA (B) and protein (C) expression in ovarian tissues was measured using qRT-PCR and western blotting. D GIMAP7 expression in ovarian tissues was measured using IHC staining. Differences between two groups were analysed using Student’s t-test. *P < 0.05, **P < 0.01, ***P < 0.001

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Journal of Ovarian Research

ISSN: 1757-2215

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