Table 5 Functional enrichment analysis for candidate genes screened from TCGA-ovarian cancer
From: SLFN5 promotes reversible epithelial and mesenchymal transformation in ovarian cancer
Pathway | Count | Molecules in network | P values |
|---|---|---|---|
GO:0070124:Mitochondrial translational initiation | 5 | MRPS16,MRPL12,MRPL11,MRPL21,CHCHD1 | 0.00886 |
GO:0070125:Mitochondrial translational elongation | 5 | MRPS16,MRPL12,MRPL11,MRPL21,CHCHD1 | 0.00886 |
GO:0070126:Mitochondrial translational termination | 5 | MRPS16,MRPL12,MRPL11,MRPL21,CHCHD1 | 0.00101 |
GO:0009595:Detection of biotic stimulus | 4 | NLRP3,TLR1,TLR6,TLR2 | 0.00191 |
GO:0006413:Translational initiation | 13 | FAU,RBM4,POLR2G,NLRP3,TLR1,TLR6,TLR2,MRPL33,MRPS16,MRPL12,MRPL11,MRPL21,CHCHD1 | 0.00256 |
GO:0032490:Detection of molecule of acterial origin | 3 | TLR1,TLR6,TLR2 | 0.00243 |
GO:0032635:Interleukin-6 production | 6 | GSTP1,ASH1L,PTAFR,TLR1,TLR6,TLR2 | 0.00373 |
GO:0002674:Negative regulation of acute inflammatory response | 3 | GSTP1,ASSH1L,NLRP3 | 0.00393 |
GO:0032755:Positive regulation of interleukin-6 production | 5 | PTAFR,LGALS9,TLR1,TLR6,TLR2 | 0.00417 |
GO:0032543:Mitochondrial translation | 6 | MRPL33,MRPS16,MRPL12,MRPL11,MRPL21,CHCHD1 | 0.00585 |