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Table 2 Clinical outcomes of the LHOTD tertile groups with agonist and antagonist regimens

From: LH level on ovulation trigger day has a different impact on the outcomes of agonist and antagonist regimens during in vitro fertilization

Variables

Agonist regimen

Antagonist regimen

T1 (< 0.56)

N = 2113

T2 (0.56–0.84)

N = 2159

T3 (> 0.84)

N = 2186

P-value

T1 (< 1.98)

N = 956

T2 (1.98–3.61)

N = 959

T3 (> 3.61)

N = 961

P-value

Number of oocytes retrieved

11.04 ± 4.45 a

10.88 ± 4.34 a

10.57 ± 4.34 b

0.001

9.00 ± 4.74 a

8.22 ± 4.51 b

7.23 ± 4.35 c

 < 0.001

2PN rate

57.1 (41.2–71.4)

55.6 (40–71.4)

57.1 (40–71.4)

0.396

52.9 (38.5–70.0)

55.6 (40.0–75.0)

55.6 (38.5–75.0)

0.062

Number of embryos transferred, n (% of total)

 1

258 (12.2)

255 (11.8)

276 (12.6)

0.714

175 (18.3) a

186 (19.4) a

235 (24.5) b

0.002

 2

1855 (87.8)

1904 (88.2)

1910 (87.4)

781 (81.7) a

773 (80.6) a

726 (75.5) b

Clinical pregnancy, n (% of ET cycles)

875 (41.4)

985 (45.6)

1083 (49.5)

 < 0.001

344 (36.0)

370 (38.6)

369 (38.4)

0.424

 Ectopic pregnancy, n (% of clinical pregnancy)

38 (4.3)

43 (4.4)

28 (2.6)

0.050

21 (6.1)

17 (4.6)

21 (5.7)

0.653

 Early pregnancy loss, n (% of clinical pregnancy)

112 (12.8)

115 (11.7)

109 (10.1)

0.159

45 (13.1)

48 (13.0)

53 (14.4)

0.829

 Ongoing pregnancy, n (% of clinical pregnancy)

730 (83.4)

831 (84.4)

953 (88)

0.009

279 (81.1)

307 (83.0)

297 (80.5)

0.664

Live births, n (% of ET cycles)

697 (33.0)

783 (36.3)

913 (41.8)

 < 0.001

265 (27.7)

286 (29.8)

281 (29.2)

0.578

  1. T1, T2, and T3 are the 1st, 2nd, and 3rd LHOTD tertile groups in two regimens, respectively
  2. The superscript characters a, b, and c represent pairwise comparisons between two groups of the same character, with no significant difference
  3. 2PN 2 pronuclear, ET Embryo transfer