LH level on ovulation trigger day has a different impact on the outcomes of agonist and antagonist regimens during in vitro fertilization

Table 3 Stepwise multivariate logistic regression of the clinical pregnancy and live birth rates with the agonist regimen

Groups	Univariate regression		Model 1		Model 2		Model 3
Groups	Crude OR	P-value	Adjusted OR (95% CI)	P-value	Adjusted OR (95% CI)	P-value	Adjusted OR (95% CI)	P-value
Clinical pregnancy (Reference T1 [< 0.56, n = 2113])
T2 (0.56–0.84, n = 2159)	1.187 (1.052–1.340)	0.006	1.167 (1.033–1.318)	0.013	1.172 (1.037–1.324)	0.011	1.187 (1.047–1.345)	0.007
T3 (> 0.84, n = 2186)	1.389 (1.231–1.567)	< 0.001	1.353 (1.198–1.529)	< 0.001	1.366 (1.208–1.544)	< 0.001	1.420 (1.252–1.610)	< 0.001
Live birth (Reference T1 [< 0.56, n = 2113])
T2 (0.56–0.84, n = 2159)	1.156 (1.019–1.312)	0.024	1.129 (0.994–1.283)	0.062	1.137 (1.001–1.292)	0.049	1.149 (1.009–1.309)	0.036
T3 (> 0.84, n = 2186)	1.457 (1.287–1.650)	< 0.001	1.408 (1.241–1.597)	< 0.001	1.423 (1.254–1.615)	< 0.001	1.476 (1.296–1.681)	< 0.001

Model 1: Age, BMI, AMH, and AFC
Model 2: Model 1, primary or secondary infertility, cause of female infertility (reference to normal), and history of parturition or miscarriage
Model 3: Model 2, indicators on the day of ovulation trigger (progesterone, estradiol, endometrial thickness), number of oocytes retrieved, fertilization method, 2PN rate, and number of embryos of transferred
T1, T2, and T3 are the 1^st, 2^nd and 3^rd LHOTD tertile groups in the agonist regimen, respectively
OR Odds ratio, CI Confidence interval

ISSN: 1757-2215