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Table 4 Mantel‒Haenszel stratification analysis of the impact of the LHOTD on the clinical outcomes and live birth rates

From: LH level on ovulation trigger day has a different impact on the outcomes of agonist and antagonist regimens during in vitro fertilization

Groups

N

Clinical pregnancy (Reference T1)

Live birth (Reference T1)

T2 Crude OR (95% CI)

P-value

T3 Crude OR (95% CI)

P-value

T2 Crude OR (95% CI)

P-value

T3 Crude OR (95% CI)

P-value

Age, years

 < 35

1795

1.316 (1.051–1.648)

0.017

1.354 (1.077–1.703)

0.009

1.275 (1.008–1.611)

0.043

1.269 (0.999–1.611)

0.051

 35–39

745

1.001 (0.678–1.478)

0.998

0.972 (0.662–1.429)

0.886

1.047 (0.677–1.62)

0.836

1.112 (0.726–1.703)

0.627

 > 39

336

0.857 (0.41–1.79)

0.682

1.071 (0.535–2.146)

0.846

0.939 (0.365–2.417)

0.897

0.989 (0.399–2.452)

0.981

BMI

 < 18.5

218

0.76 (0.393–1.471)

0.416

2.116 (1.088–4.113)

0.027

0.884 (0.438–1.785)

0.732

1.651 (0.831–3.279)

0.152

 18.5–24.9

2122

1.08 (0.87–1.34)

0.487

1.037 (0.834–1.288)

0.744

1.016 (0.806–1.281)

0.890

1.007 (0.799–1.271)

0.951

 > 24.9

536

1.515 (0.979–2.344)

0.062

1.195 (0.775–1.841)

0.420

1.714 (1.077–2.729)

0.023

1.235 (0.774–1.972)

0.376

AMH, ng/mL

 < 1.1

612

0.795 (0.503–1.257)

0.327

1.186 (0.78–1.804)

0.424

0.784 (0.478–1.287)

0.336

1.203 (0.769–1.882)

0.418

 ≥ 1.1

2264

1.219 (0.995–1.494)

0.057

1.108 (0.899–1.366)

0.334

1.204 (0.969–1.495)

0.094

1.053 (0.841–1.318)

0.652

AFC

 < 7

772

1.011 (0.656–1.558)

0.962

1.281 (0.854–1.92)

0.232

1.554 (0.933–2.588)

0.090

1.7 (1.045–2.768)

0.033

 ≥ 7

2104

1.211 (0.983–1.492)

0.072

1.179 (0.952–1.46)

0.132

1.100 (0.883–1.369)

0.396

1.088 (0.869–1.362)

0.463

Number of oocytes retrieved

 < 4

480

0.990 (0.576–1.702)

0.971

1.073 (0.648–1.776)

0.784

0.951 (0.526–1.72)

0.867

1.020 (0.589–1.767)

0.944

 4–10

1580

1.171 (0.909–1.507)

0.222

1.157 (0.898–1.489)

0.259

1.168 (0.891–1.532)

0.262

1.166 (0.889–1.529)

0.266

 > 10

816

1.197 (0.867–1.655)

0.275

1.378 (0.973–1.952)

0.071

1.177 (0.839–1.652)

0.346

1.206 (0.837–1.738)

0.314

Number of embryos transferred

 1

596

1.115 (0.655–1.898)

0.689

1.320 (0.804–2.166)

0.272

1.200 (0.677–2.128)

0.533

1.121 (0.647–1.943)

0.683

 2

2280

1.138 (0.93–1.392)

0.211

1.159 (0.944–1.422)

0.158

1.110 (0.896–1.374)

0.339

1.141 (0.919–1.417)

0.232

  1. BMI Body mass index, LH Luteinizing hormone, AMH Anti-Müllerian hormone, AFC Antral follicular count, OR Odds ratio, CI Confidence interval
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Journal of Ovarian Research

ISSN: 1757-2215

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