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Table 5 Stepwise multivariate logistic regression of the clinical pregnancy and live birth rates with the subdivided T1 LHOTD groups with the antagonist regimen

From: LH level on ovulation trigger day has a different impact on the outcomes of agonist and antagonist regimens during in vitro fertilization

Groups

Univariate regression

Model 1

Model 2

Model 3

Crude OR

P-value

Adjusted OR (95% CI)

P-value

Adjusted OR (95% CI)

P-value

Adjusted OR (95% CI)

P-value

Clinical pregnancy (Reference t1 (< 1.06, n = 314))

 t2 (1.06–1.50, n = 310)

1.112 (0.796–1.554)

0.533

1.175 (0.834–1.654)

0.356

1.145 (0.808–1.622)

0.446

1.204 (0.843–1.721)

0.307

 t3 (> 1.50, n = 332)

1.584 (1.147–2.187)

0.005

1.720 (1.231–2.402)

0.001

1.616 (1.151–2.27)

0.006

1.693 (1.194–2.4)

0.003

Live birth (Reference t1 (< 1.06, n = 314))

 t2 (1.06–1.50, n = 310)

1.088 (0.760–1.559)

0.645

1.167 (0.807–1.689)

0.412

1.141 (0.784–1.662)

0.490

1.198 (0.818–1.754)

0.354

 t3 (> 1.50, n = 332)

1.400 (0.991–1.976)

0.056

1.562 (1.09–2.237)

0.015

1.484 (1.031–2.136)

0.034

1.532 (1.057–2.22)

0.024

  1. Model 1: Age, BMI, AMH, and AFC
  2. Model 2: Model 1, primary or secondary infertility, cause of female infertility (reference to normal), and history of parturition or miscarriage
  3. Model 3: Model 2, indicators on the day of ovulation trigger (progesterone, estradiol, endometrial thickness), number of oocytes retrieved, fertilization method, 2PN rate, and number of embryos of transferred
  4. t1, t2, and t3 are the 1st, 2nd and 3rd sub-divided tertile of T1 LHOTD group in the antagonist regimen, respectively
  5. OR Odds ratio, CI Confidence interval