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Table 4 The NRI, IDI, and C-index of the nomograms and AJCC Stage system in OS and CSS prediction for elderly patients with EOC

From: Nomograms for predicting overall survival and cancer-specific survival in elderly patients with epithelial ovarian cancer

Index

Training cohort

P

Validation cohort

P

Estimate

95%CI

Estimate

95%CI

NRI (vs. AJCC Stage system)

 For 3-year OS

0.220

0.173–0.250

 

0.207

0.147–0.279

 

 For 5-year OS

0.217

0.189–0.248

 

0.204

0.149–0.256

 

 For 10-year OS

0.163

0.125–0.230

 

0.165

0.087–0.261

 

 For 3-year CSS

0.230

0.194–0.259

 

0.192

0.154–0.269

 

 For 5-year CSS

0.265

0.227–0.315

 

0.204

0.150–0.276

 

 For 10-year CSS

0.247

0.180–0.298

 

0.190

0.135–0.294

 

IDI (vs. AJCC Stage system)

 For 3-year OS

0.047

0.035–0.059

 < 0.001

0.035

0.020–0.057

 < 0.001

 For 5-year OS

0.058

0.047–0.072

 < 0.001

0.042

0.029–0.062

 < 0.001

 For 10-year OS

0.047

0.035–0.067

 < 0.001

0.033

0.010–0.061

 < 0.001

 For 3-year CSS

0.041

0.031–0.055

 < 0.001

0.036

0.024–0.062

 < 0.001

 For 5-year CSS

0.056

0.041–0.074

 < 0.001

0.046

0.030–0.067

 < 0.001

 For 10-year CSS

0.053

0.037–0.075

 < 0.001

0.043

0.025–0.074

 < 0.001

C-index

 The nomogram (OS)

0.713

0.701–0.725

 

0.751

0.731–0.771

 

 The nomogram (CSS)

0.729

0.717–0.741

 

0.702

0.680–0.724

 

 The AJCC Stage (OS)

0.513

0.495–0.531

 

0.486

0.461–0.512

 

 The AJCC Stage (CSS)

0.492

0.476–0.508

 

0.500

0.477–0.524