Fig. 1

Characterization of exosomes and their DE-miRNAs (A) A2780 exo and A2780/DDP exo were identified through TEM to have diameters of 30–130 nm (Scale bar, 100 nm). B Volcano plot of differentially expressed miRNAs. Red indicates the upregulated miRNAs between A2780 exo and A2780/DDP exo, green indicates the downregulated miRNAs, and black indicates that no difference in expression. C Hierarchical heatmap showing differential miRNA expression identified by high-throughput sequencing (HTS). Red and green indicate the different expression levels in the colour scale