Fig. 1

Estrous cycle changes and alterations of serum hormones in two representative mice from the control and PCOS groups. A, B P: proestrus; E: estrus; M: metestrus; D: dioestrus; C The body weight of mice in both groups was calculated; D Organ mass ratio of ovary to body weight; E-G Statistics of serum testosterone, LH and FSH content. H Ratio of LH to FSH. I Representative images of ovarian sections. Scale bars: 200 μm. The asterisk (*) represents the corpus luteum, and the pound sign (#) represents the ovary vacuoles. Data are expressed as the mean ± SD, *p < 0.05 vs. control