Skip to main content

Table 1 Clinical characteristics of patients

From: Timing of interval debulking surgery and postoperative chemotherapy after neoadjuvant chemotherapy in advanced epithelial ovarian cancer: a multicenter real-world study

 

Total (N = 658)

Age (years, median (IQR))

54.00 (48.00, 61.00)

Menopause

Yes

406 (61.7)

No

231 (35.1)

Unknown

21 (3.2)

BMI (kg/m2, median (IQR))

22.52 (20.55, 24.63)

Comorbidity

Yes

228 (34.7)

No

430 (65.3)

Type

Serous

555 (84.3)

Other

103 (15.7)

Grade

High

553 (84.0)

Other

105 (16.0)

FIGO stage

IIIC

423 (64.3)

IV

235 (35.7)

CA125 (U/ml, median (IQR))

1395.70 (638.50, 3180.00)

Ascites

Yes

537 (81.6)

No

114 (17.3)

Unknown

7 (1.1)

Operation time (mins, median (IQR))

203.00 (160.00, 280.00)

Blood loss (ml, median (IQR))

300.00 (200.00, 600.00)

Surgical procedure

Upper abdominal surgery

75 (11.4)

Bowel resection

90 (13.7)

Lymphadenectomy

343 (52.1)

Residual disease

R0

297 (45.1)

R1

240 (36.5)

R2

121 (18.4)

Postoperative complication

Yes

333 (50.6)

No

325 (49.4)

Hospitalization (days, median (IQR))

16 (14, 20)

NACT cycles (median (IQR))

2 (2, 3)

Chemotherapy regimen

Platinum + Paclitaxel

646 (98.2)

Other

12 (1.8)

Total cycles (median (IQR))

7 (6, 9)

  1. Abbreviation: IQR, Interquartile range; BMI, Body mass index; FIGO, International Federation of Gynecology and Obstetrics; CA125, Cancer antigen 125; NACT, Neoadjuvant chemotherapy; Total cycles, the total number of cycles of both neoadjuvant chemotherapy and postoperative adjuvant chemotherapy