Table 2 Univariate and multivariate analyses for PFS and OS based on TTS

Age, years

< 54

1 (Reference)

1 (Reference)

1 (Reference)

1 (Reference)

≥ 54

1.02 (0.85–1.23)

0.827

0.98 (0.81–1.18)

0.804

1.18 (0.93–1.49)

0.175

1.10 (0.86–1.40)

0.440

Type

Serous

1 (Reference)

1 (Reference)

1 (Reference)

1 (Reference)

Other

1.24 (0.96–1.60)

0.098

0.89 (0.68–1.18)

0.421

1.15 (0.84–1.59)

0.385

0.93 (0.66–1.31)

0.679

Grade

Other

1 (Reference)

1 (Reference)

1 (Reference)

1 (Reference)

High

1.25 (0.98–1.60)

0.077

1.15 (0.88–1.51)

0.301

1.06 (0.78–1.44)

0.709

0.99 (0.71–1.37)

0.947

FIGO Stage

IIIC

1 (Reference)

1 (Reference)

1 (Reference)

1 (Reference)

IV

0.97 (0.80–1.17)

0.741

0.86 (0.70–1.05)

0.139

1.01 (0.79–1.3)

0.935

0.91 (0.71–1.18)

0.483

Residual disease

R0

1 (Reference)

1 (Reference)

1 (Reference)

1 (Reference)

R1

1.52 (1.24–1.87)

< 0.001

1.58 (1.28–1.95)

< 0.001

1.52 (1.16–1.99)

0.002

1.55 (1.17–2.04)

0.002

R2

1.61 (1.25–2.08)

< 0.001

1.69 (1.30–2.20)

< 0.001

1.89 (1.37–2.59)

< 0.001

1.99 (1.43–2.76)

< 0.001

NACT cycle

≤ 3

1 (Reference)

1 (Reference)

1 (Reference)

1 (Reference)

> 3

1.08 (0.86–1.36)

0.509

1.17 (0.93–1.49)

0.187

1.06 (0.79–1.42)

0.714

1.12 (0.83–1.52)

0.448

TTS

≤ 25

1 (Reference)

1 (Reference)

1 (Reference)

1 (Reference)

> 25

1.16 (0.96–1.39)

0.118

1.15 (0.96–1.39)

0.141

1.34 (1.06–1.70)

0.014

1.34 (1.05–1.70)

0.018