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Table 3 Multiple models for PFS and OS based on TTS

From: Timing of interval debulking surgery and postoperative chemotherapy after neoadjuvant chemotherapy in advanced epithelial ovarian cancer: a multicenter real-world study

 

PFS

OS

 

HR (95%CI)

P value

HR (95%CI)

P value

TTS a

    

≤ 20

1 (Reference)

 

1 (Reference)

 

21–25

1.15 (0.89–1.48)

0.283

1.27 (0.91–1.77)

0.169

26–29

1.24 (0.95–1.62)

0.115

1.56 (1.09–2.21)

0.014

> 29

1.24 (0.94–1.62)

0.125

1.49 (1.05–2.12)

0.027

TTS b

1.003 (0.997–1.010)

0.288

1.010 (1.002–1.018)

0.018

P  for trend c

 

0.103*

 

0.016*

  1. Abbreviation: PFS, Progression-free survival; OS, Overall survival; TTS, Time to interval debulking surgery after the completion of neoadjuvant chemotherapy; HR, Hazard ratio; CI, Confidence interval; *, P value for Ptrend
  2. a Adjusted for age, type, grade, stage, residual disease, cycle of neoadjuvant chemotherapy and TTS (included as a quartile categorical variable)
  3. b Adjusted for age, type, grade, stage, residual disease, cycle of neoadjuvant chemotherapy and TTS (included as a continuous variable)
  4. c Adjusted for age, type, grade, stage, residual disease and cycle of neoadjuvant chemotherapy