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Table 5 Multiple models for PFS and OS based on TTC

From: Timing of interval debulking surgery and postoperative chemotherapy after neoadjuvant chemotherapy in advanced epithelial ovarian cancer: a multicenter real-world study

 

PFS

OS

 

HR (95%CI)

P value

HR (95%CI)

P value

TTC a

    

≤ 33

1 (Reference)

 

1 (Reference)

 

34–40

1.18 (0.91–1.52)

0.221

1.57 (1.10–2.23)

0.012

41–49

1.18 (0.90–1.53)

0.227

1.85 (1.31–2.62)

0.001

> 49

1.15 (0.87–1.51)

0.338

1.51 (1.03–2.19)

0.033

TTC b

1.003 (0.997–1.009)

0.333

1.009 (1.002–1.017)

0.011

P for trendc

 

0.381*

 

0.031*

  1. Abbreviation: PFS, Progression-free survival; OS, Overall survival; TTC, Time to postoperative adjuvant chemotherapy after the completion of neoadjuvant chemotherapy; HR, Hazard ratio; CI, Confidence interval; *, P value for Ptrend
  2. a Adjusted for age, type, grade, stage, upper abdominal surgery, bowel resection, lymphadenectomy, residual disease, postoperative complication, cycle of neoadjuvant chemotherapy and TTC (included as a quartile categorical variable)
  3. b Adjusted for age, type, grade, stage, upper abdominal surgery, bowel resection, lymphadenectomy, residual disease, postoperative complication, cycle of neoadjuvant chemotherapy and TTC (included as a continuous variable)
  4. c Adjusted for age, type, grade, stage, upper abdominal surgery, bowel resection, lymphadenectomy, residual disease, postoperative complication and cycle of neoadjuvant chemotherapy