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Table 3 Comparison of AFC, ovarian volume and hormonal test at baseline and after 4 months of treatment in the DHEA group

From: Dehydroepiandrosterone supplementation and the impact of follicular fluid metabolome and cytokinome profiles in poor ovarian responders

Parametersa

4-month

Baseline

Relative mean difference, RMDb

p-value

(n = 24)

(n = 24)

(95% CI)

Basal FSH (IU/L)

6.8 (1.2–24.2)

8.7 (4.8–27.7)

0.78 (0.61–1.00)

0.052

Estradiol (pmol/L)

141.8 (56.0–290.0)

94.3 (37.0–320.0)

1.50 (1.24–1.83)

 < 0.001

AMH (ng/ml)

0.6 (0.2–2.0)

0.6 (0.2–2.8)

0.99 (0.71–1.36)

0.932

Free Testosterone (pmol/L)

4.6 (2.0–9.5)

2.1 (0.8–14.3)

2.25 (1.74–2.91)

 < 0.001

DHEA-S (umol/L)

14.3 (4.5–31.2)

4.3 (0.8–17.3)

3.35 (2.42–4.63)

 < 0.001

Antral follicle count

4.4 (1–11)

4.6 (1–15)

0.96 (0.65–1.44)

0.854

Ovarian volume RO (cm3)

5.5 (0.9–14.3)

7.0 (1.9–24.0)

0.74 (0.47–1.16)

0.176

Ovarian volume LO (cm3)

5.2 (1.6–16.8)

4.8 (1.8–10.6)

1.10 (0.84–1.43)

0.472

  1. a Summarized by geometric mean (range)
  2. b Ratio of geometric means