Fig. 5

Overexpression of SOX9 or inhibition of miR-497-5p rescues OC cell proliferation and migration under silencing of circ-PHC3. A, B CCK-8 assay showing the proliferative ability of OV90 and SKOV3 cells. Data are expressed as means ± SD. ^***P < 0.001 vs NC. C-E Clone formation assays showing the proliferation ability of OV90 and SKOV3 cells. Data are expressed as means ± SD. ^***P < 0.001 vs NC. ^###P < 0.001 vs. si-circ-PHC3. F–H Transwell detection of the invasion and migration abilities of OV90 and SKOV3 cells. Data are expressed as means ± SD. ^***P < 0.001 vs NC. ^###P < 0.001 vs. si-circ-PHC3