Fig. 6

Overexpression of SOX9 rescues OC cell proliferation and migration under conditions of miR-497-5p overexpression. A-D RT-qPCR showing expression patterns of miR-497-5p and SOX9 in OV90 and SKOV3 cells. E, F CCK-8 assay of the proliferation ability of OV90 and SKOV3 cells. Data are expressed as means ± SD. ^***P < 0.001 vs NC. G-I Clone formation assay showing the proliferation ability of OV90 and SKOV3 cells. Data are expressed as means ± SD. ^*P < 0.05, ^***P < 0.001 vs NC. ^###P < 0.001 vs. miR-497-5p mimic. J-L Transwell detection assay of the invasion and migration capabilities of OV90 and SKOV3 cells. Data are expressed as means ± SD. ^*P < 0.05, ^***P < 0.001 vs NC. ^###P < 0.001 vs miR-497-5p mimic