Table 1 Comparison of baseline characteristics of model cohort and validation cohort
Parameter | Stratification | Total | Model dataset | Validation dataset | Test_value | P_value |
|---|---|---|---|---|---|---|
Survival_status[n(%)] | Survival | 14,583 | 8742(28.89) | 5841(19.31) | 0.81 | 0.367 |
Dead | 15,672 | 9314(30.78) | 6358(21.01) | |||
Stage[n(%)] | Stage I | 8583 | 5091(16.83) | 3492(11.54) | 0.92 | 0.821 |
Stage II | 3325 | 1999(6.61) | 1326(4.38) | |||
Stage III | 12,940 | 7724(25.53) | 5216(17.24) | |||
Stage IV | 5407 | 3242(10.72) | 2165(7.16) | |||
PT[n(%)] | T1 | 9128 | 5411(17.88) | 3717(12.29) | 0.95 | 0.621 |
T2 | 4387 | 2634(8.71) | 1753(5.79) | |||
T3 | 16,740 | 10,011(33.09) | 6729(22.24) | |||
PN[n(%)] | No | 23,238 | 13,861(45.81) | 9377(30.99) | 0.04 | 0.85 |
Yes | 7017 | 4195(13.87) | 2822(9.33) | |||
PM[n(%)] | No | 24,848 | 14,814(48.96) | 10,034(33.16) | 0.2 | 0.654 |
Yes | 5407 | 3242(10.72) | 2165(7.16) | |||
Radiation[n(%)] | No | 29,771 | 17,762(58.71) | 12,009(39.69) | 0.19 | 0.664 |
Yes | 484 | 294(0.97) | 190(0.63) | |||
Chemotherapy[n(%)] | No | 7009 | 4145(13.7) | 2864(9.47) | 1.08 | 0.298 |
Yes | 23,246 | 13,911(45.98) | 9335(30.85) | |||
Surgery[n(%)] | No | 567 | 355(1.17) | 212(0.7) | 1.94 | 0.164 |
Yes | 29,688 | 17,701(58.51) | 11,987(39.62) | |||
Grade[n(%)] | Moderately differentiated | 3527 | 2131(7.04) | 1396(4.61) | 5.34 | 0.148 |
Poorly differentiated | 5752 | 3359(11.1) | 2393(7.91) | |||
Undifferentiated | 13,612 | 8141(26.91) | 5471(18.08) | |||
Well differentiated | 7364 | 4425(14.63) | 2939(9.71) | |||
Race[n(%)] | White | 25,328 | 15,086(49.86) | 10,242(33.85) | 1.62 | 0.656 |
Black | 1893 | 1128(3.73) | 765(2.53) | |||
Asian or Pacific Islander | 2814 | 1706(5.64) | 1108(3.66) | |||
American Indian/Alaska Native | 220 | 136(0.45) | 84(0.28) | |||
Laterality[n(%)] | Left | 8538 | 5131(16.96) | 3407(11.26) | 1.81 | 0.405 |
Right | 8538 | 5047(16.68) | 3491(11.54) | |||
Both | 13,179 | 7878(26.04) | 5301(17.52) | |||
Schedule[n(%)] | Without Treatment | 146 | 104(0.34) | 42(0.14) | 14.06 | 0.05 |
Chemotherapy only | 406 | 241(0.8) | 165(0.55) | |||
Radiation only | 5 | 2(0.01) | 3(0.01) | |||
Radiation + Chemotherapy | 10 | 8(0.03) | 2(0.01) | |||
Surgery only | 6803 | 4010(13.25) | 2793(9.23) | |||
Chemotherapy + Surgery | 22,416 | 13,407(44.31) | 9009(29.78) | |||
Radiation + Surgery | 55 | 29(0.1) | 26(0.09) | |||
Three therapy | 414 | 255(0.84) | 159(0.53) | |||
Survival_month [month]a | 60.0(29.0,103.0) | 59.0(29.0,101.0) | 60.0(29.0,105.0) | 108,724,809.5 | 0.059 | |
Age [year]a | 58.0(50.0,67.0) | 58.0(50.0,67.0) | 58.0(50.0,67.0) | 110,041,017 | 0.902 |