From: SPON1 is an independent prognostic biomarker for ovarian cancer
Variable | HR | 95% CI | P-value | |
---|---|---|---|---|
Age | ≥ 60 | 1.337 | 0.878–2.036 | 0.175 |
FIGO Stage | III/IV | 6.215 | 3.760–10.271 | < 0.001 |
Histological type | HGSC | 3.602 | 2.320–5.592 | < 0.001 |
T classification (pT) | 2/3 | 6.233 | 3.566–10.897 | < 0.001 |
Lymph node metastasis | (+) | 2.490 | 1.392–4.455 | 0.002 |
Distant metastasis | (+) | 4.345 | 2.528–7.466 | < 0.001 |
Peritoneal dissemination | (+) | 5.945 | 3.719–9.502 | < 0.001 |
Ascites cytoloy | (+) | 3.731 | 2.032–6.848 | < 0.001 |
Type of surgery | Suboptimal | 5.927 | 3.667–9.581 | 0.015 |
CA-125 (U/mL) | ≥ 35 | 2.812 | 1.226–6.447 | 0.014 |
Platinum sensitivity | Resistance | 4.893 | 2.935–8.159 | < 0.001 |
Neoadjuvant chemotherapy | (+) | 3.261 | 1.883–5.649 | < 0.001 |
SPON1 | High | 3.567 | 2.085–6.105 | < 0.001 |