Fig. 5
From: BCAS2 regulates granulosa cell survival by participating in mRNA alternative splicing
Loss of BCAS2 in granulosa cells leads to DNA damage and increased apoptosis. A, C Images of PfGC-Bcas2+/+ and PfGC-Bcas2−/− ovaries were obtained at 7 dpp, 10 dpp, and 14 dpp and stained with anti-γ-H2AX and TUNEL. Scale bars, 50 μm. B, D The positive cell rate of γ-H2AX and TUNEL was counted at different times. Student’s t test was used for this study. Data are expressed as the means ± SEMs in at least three independent experiments. * P < 0.05, ** P < 0. 01, *** P < 0.001